SYNERGISTIC EFFECTS OF BACTERIOPHAGE COCKTAIL AND ANTIBIOTICS COMBINATIONS AGAINST EXTENSIVELY DRUG-RESISTANT ACINETOBACTER BAUMANNII

Synergistic effects of bacteriophage cocktail and antibiotics combinations against extensively drug-resistant Acinetobacter baumannii

Abstract Background The extensively drug-resistant (XDR) strains of Acinetobacter baumannii have become a major cause of nosocomial infections, increasing morbidity and mortality worldwide.Many different treatments, including phage therapy, are attractive ways to overcome the challenges of antibiotic resistance.Methods This study investigates the b

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The utility of Ki-67 as a prognostic biomarker in pulmonary neuroendocrine tumours: protocol for a systematic review and meta-analysis

Introduction The omission of the immunohistochemical proliferation marker Ki-67 labelling index (henceforth, simply Ki-67) from the 2015 WHO classification system of pulmonary neuroendocrine tumours Holders (Lung-NETs) as a prognostic and grading criterion remains controversial.This systematic review along with meta-analysis will be conducted to as

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Mitochondrial dysfunction in diabetic nephropathy: insights and therapeutic avenues from traditional Chinese medicine

Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus.The progressive damage to glomeruli, tubules, and interstitium in the kidneys can lead to the development of chronic kidney disease (CKD) and end-stage renal disease (ESRD).Most of the energy we need comes from mitochondria.Mitochondria are best known as the sites for pr

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